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Feeling a little stressed out lately? Well.. you may want to try to RELAX because stress, or chronic stress, is your brain's worst enemy; impairing memory, learning and decision making. Stress has been shown to lead to significant brain volume loss in the hippocampus and the prefrontal cortex while also strengthening connections in the amygdala. Hyperactivity in the amygdala is believed to increase anxiety like behaviours. In this video I describe how glucocorticoids travel through the blood brain barrier; increasing glutamate levels in the brain which is believed to be "neurotoxic" and accelerate the brain ageing process. But why do some people thrive while others struggle under the same stressful conditions? I'll cover that too :) If you enjoyed this video, I would be super grateful if you gave this video a thumbs up and leave a comment telling me what you thought of everything I mentioned in the video. AND OBV DON'T FORGET TO SUBSCRIBE specially if you would like to see my video on how exercise helps to prevent or relieve much of the brain damage caused by chronic stress. This video is part one of a three part series. Check the links below to watch the other two parts: (Pt 2) Exercise To Improve & Protect Brain Function • WHY EXERCISE.. The Best Way To Improv... (Pt 3) Brain Fog Explained & ISRIB To The Rescue • BRAIN FOG EXPLAINED; Could ISRIB REAL... Check out the following links to my social media accounts: / neurontheorymd / neurontheorymd / neurontheorymd Substack Newsletter https://doctortellmewhy.substack.com/ References https://pubmed.ncbi.nlm.nih.gov/29421... https://pubmed.ncbi.nlm.nih.gov/28856... https://pubmed.ncbi.nlm.nih.gov/32326... ... Chapters 0:00 Intro, Stressful Times We're Living In 1:17 How Glucocorticoids, Stress Hormones, Affect The Brain 2:34 Structural Brain Changes (Prefrontal Cortex + Hippocampus) 3:41 Glutamate; The Brain's Excitatory Neurotransmitter 4:48 The Amygdala Response To Stress 5:39 Reactive Genes, Why Some Thrive, Others Struggle 7:53 Brain Ageing, Cognitive Decline 8:38 Outro, Subscribe, Exercise For Prevention #Stress #ChronicStress #HumanBrain #StressedOutBrain