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Check for more details: http://esot2017.esot.org/ A lot of things are changing. At that time, it's difficult to get this perception. Slow science is a perception in some way because we have collected in the last decade a small but commutative contributions in the science of transplantation. When we have enough cumulative contributions, at the end, this quantitative phenomenon translates to a qualitative one. We are ready to jump. A lot of things are changing. At times, it's difficult to get this perception when you are in your daily life trying to fight against problems and new challenges derived from the most complicated clinical care patients. We have to be very optimistic because we are almost there. This video is part of a series to promote the upcoming congress for the European Society of Organ Transplantation (ESOT) in Barcelona; September 24th to 27th 2017. We would like to invite you to a new level of medical meetings in transplantation at the BigBangBarcelona conference. Transplantation has emerged from the decades of an early experimental procedure to an established first line therapy for organ failure. While mechanistic devices or fully artificial organs may be available in many decades from now, the fate of the patients suffering from organ failure today and in the next many years, will depend on the progress with achieve with transplantation now. The discrepancy between the high demand and the shortage in organs available remains a challenge. Amongst the many obstacles highlighted at the congress, progress in transplantation with organs from living donors but also advancements in normothermic perfusion and other seminal technologies will be addressed. Novel drugs, protocols for immunomodulation and tolerance but also surrogate endpoints for clinical trials in order to enhance the drug development remain critically important topics in the field. The BigBangBarcelona congress might help to refine our knowledge of basic science and clinical concepts to improve transplantation in a holistic approach. Come on and join us at BigBangBarcelona. Josep Maria Grinyò and Stefan Schneeberger Scientific Program Committee Chairs