A Pig Lung Worked in a Human—for 9 Days скачать в хорошем качестве

A Pig Lung Worked in a Human—for 9 Days

Researchers transplanted a single lung from a six-gene-edited pig into a 39-year-old brain-dead human donor and monitored it for 216 hours. The organ maintained gas exchange without hyperacute rejection or infection, but developed early edema and later antibody-mediated injury that partially improved under intensive immunosuppression. The study demonstrates feasibility while highlighting major remaining challenges before any trial in living patients. Full paper title: Pig-to-human lung xenotransplantation into a brain-dead recipient. Author(s) and institutional affiliation(s): Jianxing He, Jiang Shi, Chao Yang, Guilin Peng, Chunrong Ju, Yi Zhao, Hui Liu, et al.; The First Affiliated Hospital of Guangzhou Medical University & National Clinical Research Center for Respiratory Disease (China); Chengdu Clonorgan Biotechnology (China); collaborators from Duke University (USA), Mayo Clinic (USA), Samsung Medical Center (Korea), and Nagoya University (Japan). Journal and date: Nature Medicine, 25 August 2025. DOI: https://doi.org/10.1038/s41591-025-03... #xenotransplantation #lungtransplant #organShortage #immunology #CRISPR #biotech #surgery #pulmonology #medicalresearch #ethics #China #transplantation #NatureMedicine #DailyDoseOfPapers #research #science #sciencenews #academic #papersummary #tldr #studygram #dailyresearch #sciencelovers #researchlife #scientificpapers #knowledge #datascience #ai #medicine #psychology #biology #neuroscience #climatechange