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Dr. Shams explains why Chronic Kidney Disease patients more at risk of progressive PAD or Critical Limb Ischemia. The three categories of patients that develop Peripheral Arterial Disease far down in the leg include elderly patients usually over the age of 80, patients with diabetes mellitus, and patients with chronic kidney disease. The reason Peripheral Arterial Disease is so prevalent in patients with chronic kidney disease is due to high phosphate levels and homocysteine levels. Even if patients are on dialysis, and they're getting good dialysis, they can get a particular type of disease with calcification which can form in the low part of the leg. The reason why that's of concern is because it's much easier to treat larger blood vessels. As the blood vessels get smaller and smaller, they can block up much easier. Therefore, a patient who presents with Peripheral Arterial Disease, in general, has only a 5% risk of losing their limb over the next five years. But a patient who has kidney disease and presents with Critical Limb Ischemia may actually have a 50% one-year limb loss rate. It’s critical these patients are treated. Read more at https://americanendovascular.com/are-... Schedule your consultation today at 1-833-PAD-EXPERT (1-833-723-3973).