EP46: Understanding Patient Heterogeneity in IBD with Spatial Transcriptomics скачать в хорошем качестве

EP46: Understanding Patient Heterogeneity in IBD with Spatial Transcriptomics

🔬 SCSE Club: Understanding Patient Heterogeneity in IBD with Spatial Transcriptomics 🚀 Join us this week at the SCSE Club! We will dive into the spatial transcriptomic datasets from Garrido-Trigo et al. (2023) - covering Crohn’s disease (CD), ulcerative colitis (UC), and healthy controls - using BioTuring’s SpatialX platform. We’ll cover: Differences in cell-type heterogeneity across healthy, CD, and UC samples The major contribution of myeloid cells to patient-to-patient variability Neighborhood analysis to pinpoint cell pairs whose interactions shape disease features Mapping cell–cell communication networks in IBD samples Plus, a live demo of SpatialX for: Cell-type proportion analysis Cell–cell communication on spatial transcriptomic data This session will show you how SpatialX can uncover cell-type composition and intercellular crosstalk from spatial transcriptomics - insights crucial for understanding disease progression and treatment response. 📅 Friday, August 1, 2025 🕘 9 AM CET | 4 PM JST 🔗 Register now: https://lnkd.in/gjtqyeV3 #SpatialX #CosMx #IBD #Bioinformatics #SpatialTranscriptomics #NeighborhoodAnalysis #DistanceQuery #Neutrophils #InflammatoryFibroblasts #Macrophages #SpatialDataAnalysis #CellTypeProportions #CellCellCommunication #PatientHeterogeneity