B-lymphoid transcriptional programme as a barrier against malignant transformation in acute lymp... скачать в хорошем качестве

B-lymphoid transcriptional programme as a barrier against malignant transformation in acute lymp...

Prof Markus Müschen talks to ecancer at the European School of Haematology (ESH) meeting: International Conference on Acute Lymphoblastic Leukaemia about how inhibitory phosphatases regulate the survival of B-lymphocytes. He explains how phosphatases are necessary for oncogene signalling and the inhibition of these may prevent relapse and overcome drug resistance in acute lymphoblastic leukaemia (ALL). Prof Müschen mentions the possibility of incorporating precision medicine in this approach, along with the differences between various subtypes of leukaemia. He concludes by summarising the specific therapeutic targets in this signalling pathway. Sign up to ecancer for free to receive tailored email alerts for more videos like this. ecancer.org/account/register.php ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.