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Diffuse toxic goiter - Medical Meaning and Pronunciation

Goodies: https://geni.us/medical-dictionary Title: Diffuse toxic goiter Diffuse toxic goiter: Graves disease, the most common cause of hyperthyroidism (overactivity of the thyroid gland), with generalized diffuse overactivity (toxicity) of the entire thyroid gland which becomes enlarged into a goiter. There are three clinical components to Graves disease: Graves disease can run in families. The rate of concordance for Graves disease is about 20% among monozygotic (identical) twins, and the rate is much lower among dizygotic (nonidentical) twins, indicating that genes make only a moderate contribution to the susceptibility to Graves disease. No single gene is known to cause the disease or to be necessary for its development. There are well-established associations with certain HLA types. Linkage analysis has identified gene loci on chromosomes 14q31, 20q11.2, and Xq21 that are associated with susceptibility to Graves disease. Factors that can trigger the onset of Graves disease include stress, smoking, radiation to the neck, medications (such as interleukin-2 and interferon-alpha), and infectious organisms such as viruses. The diagnosis of Graves disease is made by a characteristic thyroid scan (showing diffusely increase uptake), the characteristic triad of ophthalmopathy, dermopathy, and hyperthyroidism, or blood testing for TSI (thyroid stimulating immunoglobulin) the level of which is abnormally high. How to pronounce Diffuse toxic goiter definition of Diffuse toxic goiter audio dictionary How to say Diffuse toxic goiter What is the meaning of Diffuse toxic goiter Pronounce Diffuse toxic goiter Medical dictionary Medical definition of Diffuse toxic goiter