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Learn more about MDS at http://www.YouAndMDS.com MDS experts, Dr Rafael Bejar and Dr Casey O’Connell describe when a blood and marrow (stem cell transplant) is used for MDS-related anemia. Although stem cell transplantation represents the only cure for MDS, it is not a guarantee and the process is associated with a lot of risks. The decision to proceed with a transplant is a complicated one involving several considerations, including age, MDS risk category, and presence of co-existing diseases. Stem cell transplantation is often considered for people with high risk disease. On average, lower risk MDS patients will likely do better living with their disease and taking non-transplant treatments, rather than undergoing a stem cell transplant.