Causes and Anatomical basis for Frey's Syndrome; Damage or lesion to Auriculotemporal nerve скачать в хорошем качестве

Causes and Anatomical basis for Frey's Syndrome; Damage or lesion to Auriculotemporal nerve

Frey syndrome is a postoperative phenomenon following salivary gland surgery and less commonly neck dissection, facelift procedures, and trauma that is characterized by gustatory sweating and flushing. Frey syndrome was first described by Lucie Frey in 1923 and was termed auriculotemporal syndrome. It described sweating and flushing in the preauricular area in response to mastication or a salivary stimulus.1 Initially thought to be rare, it was later recognized as a common occurrence after salivary gland surgery, occurring in 4% to 62% of postparotidectomy patients 6 to 18 months after surgery.2–5 The synkinetic mechanism for Frey syndrome is aberrant reinnervation of postganglionic parasympathetic neurons to nearby denervated sweat glands and cutaneous blood vessels.6 Consequently, this results in flushing and sweating in the sympathetically void skin in response to mastication and salivation. The previous sympathetic responses of sweating and flushing are now controlled by postganglionic parasympathetic fibers. Mastication, which releases acetylcholine from the parasympathetic nerve endings,3,6 now induces sweating and flushing, which was a sympathetic cholinergic response before synkinesis of parasympathetic nerve fibers #freyssyndrome