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Explore our entire animation video library at: https://www.nonstopneuron.com/ All videos from endocrine physiology: https://www.nonstopneuron.com/post/ph... Video Summary: Insulin is released by β cells of the pancreas. An increase in blood glucose leads to increased glucose entry in the cell. Its metabolism produces ATPs. Increased ATP level causes closure of ATP-sensitive K channel. This leads to depolarization and thereby opening of voltage-gated Ca channels. Ca influx through these channel increases intracellular Ca which in turn causes exocytosis of insulin vesicles. ● Follow us at: • Facebook: / nonstopneuron • Instagram: / nonstopneuron DISCLAIMER: This video is for education purpose only. Although every effort is made to ensure accuracy of material, viewer should refer to the appropriate regulatory body/authorised websites, guidelines and other suitable sources of information as deemed relevant and applicable. In view of possibility of human error or changes in medical science, any person or organization involved in preparation of this work accepts no responsibility for any errors or omissions or results obtained from use of information in this video.