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vol.3/3) LH-RH Agonist or Antagonist?

(side note) LH-RH agonist: Goserelin , Leuprolide (Eligard®) LH-RH antagonist: Degarelix (Firmagon®), This 8-minute video is for medical students, packed with insights on prostate cancer care and hormone therapy. #prostatecancertreatment #hormonetherapy #pharmacology 【Study Break Oasis】 5-Min Forest Oasis: Healing Sounds for Study Stress    • 5-Min Forest Oasis: Healing Sounds for Stu...   5-Min Seaside Serenity: Waves of Calmness for Study Stress    • 5-Min Seaside Serenity: Waves of Calmness ...   【Learn about Hormone Therapy For Prostate Cancer】 vol 1/3) Why is Hormone Therapy used for Prostate Cancer?    • vol.1/3) Hormone Therapy for Prostate Canc...   vol 2/3) Androgen Receptor and Androgen Synthesis Abiraterone (ZYTIGA®, Yonsa®), Ketoconazol (Nizoral®), Flutamide (Eulexin®), Bicalutamide (Casodex®)., Mechanism    • vol.2/3) CYP 17 inhibitors?: Abiraterone, ...   vol 3/3) LH-RH agonist or antagnist? Goserelin (ZOLADEX®), Leuprolide (Eligard®, Lupron Depot®), Degarelix (Firmagon®), Mechanism    • vol.3/3) LH-RH Agonist or Antagonist?   【Learn about Hormone Therapy for Breast Cancer】 vol 1/4) Why is Hormone Therapy used for Breast cancer?    • vol.1/4) What is Hormone Therapy for Breas...   vol 2/4) SERMs: Tamoxifen (Nolvadex®, Soltamox®), Raloxifene (Evista®)    • vol.2/4) What is SERMs?   vol 3/4) Aromatase inhibitors: Anastrozole (Arimidex®), Letrozole (Femara®), Exemestane (Aromasin®),    • vol.3/4) Do you know the mechanism of acti...   vol 4/4) LH-RH agonist: Goserelin (ZOLADEX®), Leuprolide (Eligard®, Lupron Depot®)    • vol.4/4) LH-RH Agonists? NOT Antagonists?:...   Explore and master the essentials. 【Notes】 ▹This video was created based on data as of April 2024, with the purpose of supporting medical students in their exam preparations. ▹Please note that thanks to the tireless efforts of researchers worldwide, this data is updated daily. ▹Unauthorized reproduction is prohibited. 【Reference and figure】 I express my gratitude and respect for your wonderful achievements. 1. Mills, I. Maintaining and reprogramming genomic androgen receptor activity in prostate cancer. Nat Rev Cancer 14, 187–198 (2014). https://doi.org/10.1038/nrc3678 2. Watson, P., Arora, V. & Sawyers, C. Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer. Nat Rev Cancer 15, 701–711 (2015). https://doi.org/10.1038/nrc4016 3. Naamneh Elzenaty R, du Toit T, Flück CE. Basics of androgen synthesis and action. Best Pract Res Clin Endocrinol Metab. 2022 Jul;36(4):101665. doi: 10.1016/j.beem.2022.101665. Epub 2022 May 6. PMID: 35595638. 4. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Flutamide. [Updated 2023 Mar 15]. Available from: https://www.ncbi.nlm.nih.gov/books/NB... 5. DrugBank online, Bicalutamide, DB01128, https://go.drugbank.com/drugs/DB01128 6. Fagerlund A, Cormio L, Palangi L, Lewin R, Santanelli di Pompeo F, Elander A, Selvaggi G. Gynecomastia in Patients with Prostate Cancer: A Systematic Review. PLoS One. 2015 Aug 26;10(8):e0136094. doi: 10.1371/journal.pone.0136094. PMID: 26308532; PMCID: PMC4550398. 7. Biernacka-Łukanty JM, Lehmann TP, Trzeciak WH. Inhibition of CYP17 expression by adrenal androgens and transforming growth factor beta in adrenocortical cells. Acta Biochim Pol. 2004;51(4):907-17. PMID: 15625562. 8. Zhu X, Wu S. Risk of hypertension in Cancer patients treated with Abiraterone: a meta-analysis. Clin Hypertens. 2019 Apr 1;25:5. doi: 10.1186/s40885-019-0110-3. PMID: 30984412; PMCID: PMC6442407. 9. Clinton TN, Woldu SL, Raj GV. Degarelix versus luteinizing hormone-releasing hormone agonists for the treatment of prostate cancer. Expert Opin Pharmacother. 2017 Jun;18(8):825-832. doi: 10.1080/14656566.2017.1328056. Epub 2017 May 19. PMID: 28480768; PMCID: PMC7171911. 10. NIH National Cancer Institute, Hormone Therapy for Prostate cancer. https://www.cancer.gov/types/prostate... 11. Bernard Jégou, Antoine D. Rolland, Sertoli Cell, Editor(s): Michael K. Skinner, Encyclopedia of Reproduction (Second Edition), Academic Press, 2018, Pages 24-27, ISBN 9780128151457, https://doi.org/10.1016/B978-0-12-801.... (https://www.sciencedirect.com/science...) 12. Aladamat N, Tadi P. Histology, Leydig Cells. [Updated 2022 Nov 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NB...