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Watch the Full Video at https://www.jove.com/v/56365/mri-guid.... MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor - a 2 minute Preview of the Experimental Protocol Ying Meng, Yuexi Huang, Benjamin Solomon, Kullervo Hynynen, Nadia Scantlebury, Michael L. Schwartz, Nir Lipsman Sunnybrook Health Sciences Centre, Division of Neurosurgery; Sunnybrook Health Sciences Centre, Sunnybrook Research Institute; High-intensity MRI guided focused ultrasound is an emerging noninvasive technique to precisely ablate brain tissue. It has been shown to be safe and effective in treating medically-refractory essential tremor. This article describes the protocol for thalamotomy from patient selection to equipment setup to post-treatment follow-up. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments