Upper Airway Microbiome Transplantation - New Treatment for Chronic Sinus Disease? скачать в хорошем качестве

Upper Airway Microbiome Transplantation - New Treatment for Chronic Sinus Disease?

Chronic or recurrent rhinosinusitis without nasal polyps (CRSsNP) affects between 5 to 12% of the population and is characterised by persistent inflammation of the sino-nasal mucosa. Despite this common presentation, the underlying cause of the condition remains unclear. Treatment has historically relied on the use of antibiotics, anti-inflammatory drugs, and surgery. These measures do reduce symptoms temporarily, but long-term results are often unsatisfactory. We know that paranasal sinuses are not sterile in healthy individuals. They are colonised by commensal bacteria. These bacteria make up the microbiome. It now appears that disturbances in the makeup of the microbiome by pathogens or indeed by the use of antibiotics may promote chronic rhinosinusitis. Can symptoms of Chronic Rhinosinusitis (CRS) be improved by transplanting the microbiome from a healthy person? Professor Anders Cervin and Dr Anders Martensson from Sweden were our guests on this EUFOREA News Show to discuss the results of the research project undertaken. 📄 Read the Paper here: https://onlinelibrary.wiley.com/doi/e... Prof. Anders Cervin 2:15 What is the microbiome and how it differs in patients with CRS? 3:49 Tell us about the study you undertook! 4:45 Where does the healthy microbiome come from? 5:16 What did the results show? 6:00 Were you surprised by the results? Dr Anders Mårtensson 7:33 What were the practicalities involved? 8:16 What component of the healthy microbiome might be responsible for the effects seen in your study? 9:15 What are the next steps? 9:45 What needs to be done to follow up on your study and what is your prediction for the future? 10:13 What do the patients make of this? -------------------------------------------------------------------------------------------------------------------------- 📽 Subscribe to our YouTube Channel for our latest videos on Allergies and Airway Diseases http://bit.ly/3eMvc3E -------------------------------------------------------------------------------------------------------------------------- 📧 Get in touch with the EUFOREA team for any questions http://bit.ly/2OtlIQp -------------------------------------------------------------------------------------------------------------------------- 📌 EUFOREA is an international non-profit organisation aiming to implement optimal patient care for allergies and airway diseases (asthma, chronic rhinosinusitis, rhinitis) and comorbidities through education, research and advocacy. #euforea 📍Follow us on social media Twitter: http://bit.ly/38wrrM7 LinkedIn: http://bit.ly/2OqtWsf Instagram: http://bit.ly/3TGB5jM ​Facebook: http://bit.ly/3cnNyFF