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Research focused on consuming too much sorbitol discovers concerning evidence revealing how the alternative sweetener can be harmful to human health. Investigator Gary Patti, PhD, connects the dots between diet and cancer. Patti is a professor of chemistry at Washington University in St. Louis and a professor of genetics and of medicine at WashU Medicine. He’s also a research member of Siteman Cancer Center, based at Barnes-Jewish Hospital and the School of Medicine. "There’s no free lunch. Everyone is looking for the way to fulfill their sweet tooth, and not have any of the negative consequences," Patti said. His research team had previously revealed how fructose is tied to cancer. They proved how too much fructose fuels tumor growth in animal models. Next, Patti wanted to know more about alternative sweeteners. Patti’s team focused on sorbitol, a sugar alcohol that’s commonly used in sugar-free products, such as sugar-free gum, candy and desserts. It’s also found in drinks like some wines and beer. "Sweet Kool-Aid, sweet tea," he added. Sorbitol is found naturally in some fruits and vegetables. "It’s just like glucose or fructose. It has a similar kind of structure" said Patti. In cases of consuming too much sorbitol, Patti’s team made some critical discoveries. First, they found that sorbitol can be naturally produced in the gut from glucose. "The amount of glucose that's required to produce sorbitol, has to be exceptionally high," he said. "It's the bacteria in your gut that define how much of that sorbitol escapes the gut." They discovered what can happen when consumption of sorbitol becomes too much. "If it escapes the gut, because the bacteria can't clear it, the first thing that happens is sorbitol gets converted into fructose. It's just like eating high levels of fructose," he said. "You end up with high levels of fructose in your liver, which makes fructose. This is bad for cancer, metabolic disease, liver disease and diabetes." Subscribe now ➤ https://bit.ly/2NNQiyM For more great content from HEC Media check us out at: Facebook ➤ http://bit.ly/1WPZEek Twitter ➤ http://bit.ly/22qZDNU Instagram ➤ http://bit.ly/1THSOnM