Does HERV-W Cause Multiple Sclerosis? (Human Endogenous Retroviruses Explained by Neurologist) скачать в хорошем качестве

Does HERV-W Cause Multiple Sclerosis? (Human Endogenous Retroviruses Explained by Neurologist)

Human endogenous retroviruses (HERVs) are ancient retroviruses which have incorporated into the human genome. There is a surprising link between one HERV (HERV-W) and MS, and some experts have hypothesized that antiretrovirals could treat MS. But what is the evidence? This study explains HERVs, the link to MS, and antiretroviral trials. Selected Sources: Multiple sclerosis–associated retrovirus (MSRV) in Sardinian MS patients: https://n.neurology.org/content/58/3/471 Multiple sclerosis-associated retrovirus and optic neuritis: https://journals.sagepub.com/doi/10.1... Multiple sclerosis–associated retrovirus and MS prognosis An observational study: https://n.neurology.org/content/59/7/... Role of Endogenous Retroviruses in Human Genetic Diseases: https://www.researchgate.net/publicat... The Envelope Protein of a Human Endogenous Retrovirus-W Family Activates Innate Immunity through CD14/TLR4 and Promotes Th1-Like Responses: https://journals.aai.org/jimmunol/art... The Envelope Protein of a Human Endogenous Retrovirus-W Family Activates Innate Immunity through CD14/TLR4 and Promotes Th1-Like Responses: https://journals.aai.org/jimmunol/art... Long-term reinfection of the human genome by endogenous retroviruses: https://www.ncbi.nlm.nih.gov/pmc/arti... Endogenous Retroviruses: With Us and against Us: https://www.frontiersin.org/articles/... An Envelope Glycoprotein of the Human Endogenous Retrovirus HERV-W Is Expressed in the Human Placenta and Fuses Cells Expressing the Type D Mammalian Retrovirus Receptor: https://www.ncbi.nlm.nih.gov/pmc/arti... HERV-W polymorphism in chromosome X is associated with multiple sclerosis risk and with differential expression of MSRV: https://www.ncbi.nlm.nih.gov/pmc/arti... A phase II baseline versus treatment study to determine the efficacy of raltegravir (Isentress) in preventing progression of relapsing remitting multiple sclerosis as determined by gadolinium-enhanced MRI: The INSPIRE study: https://www.sciencedirect.com/science... HIV and lower risk of multiple sclerosis: beginning to unravel a mystery using a record-linked database study: https://jnnp.bmj.com/content/86/1/9.long A phase IIa randomised clinical study of GNbAC1, a humanised monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus in multiple sclerosis patients: https://pubmed.ncbi.nlm.nih.gov/25392... Comment or ask questions below! I would be happy to answer! Subscribe on YouTube for more videos every Wednesday! Make video requests in the comments section! Check out my book “Resilience in the Face of Multiple Sclerosis” FREE on Amazon: https://amazon.com/dp/B07WP7H5LK It's about 5 people with MS who live incredible lives, the science and psychology of resilience, mindfulness, and ho’oponopono. Paperback priced to generate $0 royalty. Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research. Follow me on twitter:   / brandon_beaber   Music: INNER GRACE - Copyright 2018 Wilton Vought Source: Really Really Free Music Link:    • Видео   T he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.