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In this evidence-based video, Dr. Sean Hashmi explains how your gut microbiome directly impacts kidney health and shares practical strategies to support both systems for better outcomes. ABOUT THIS VIDEO Discover the critical connection between gut bacteria and kidney disease progression. Learn why people with kidney disease have up to 50% fewer beneficial gut bacteria and how this creates a vicious cycle of inflammation and damage. Dr. Hashmi reviews the latest research on diet, supplements, and lifestyle changes that can improve this gut-kidney axis. QUICK NAVIGATION 00:00 - Introduction 01:31 - What is the gut microbiome? 03:29 - The gut-kidney connection explained 04:52 - The vicious cycle of damage 06:20 - Changes in gut microbiome with CKD 07:55 - Consequences of gut dysbiosis 09:58 - Dietary strategies for gut health 11:57 - Gut-friendly foods to focus on 14:24 - Foods to limit 15:12 - Promising supplements (consult doctor) 16:40 - Research highlights 18:07 - 8 practical action steps 19:57 - Conclusion and key takeaways KEY INSIGHTS Gut dysbiosis worsens kidney disease by increasing harmful uremic toxins and inflammation Higher levels of gut-derived toxins are linked to a 33-62% increased risk of cardiovascular events in CKD patients Plant-based diets rich in berries, fiber, and prebiotic foods support both gut and kidney health Specific prebiotics, probiotics, and synbiotics show promise - one study found a 30% reduction in harmful toxins SCIENTIFIC REFERENCES Vaziri ND et al. (2013). Chronic kidney disease alters intestinal microbial flora. Kidney Int. Lin CJ et al. (2018). The role of protein-bound uremic toxins in chronic kidney disease. Toxins (Basel). Rossi M et al. (2016). Synbiotics Easing Renal Failure by Improving Gut Microbiology (SYNERGY): A Randomized Trial. CJASN. Kidney International (2024). KDIGO Clinical Practice Guideline for CKD. Zhu H et al. (2021). The Probiotic L. casei Zhang Slows the Progression of Acute and Chronic Kidney Disease. Cell Metabolism. ABOUT DR. SEAN HASHMI Dr. Sean Hashmi is a board-certified nephrologist specializing in kidney health, lifestyle medicine, and obesity medicine. He translates complex medical research into actionable strategies to help you maintain healthy kidneys and improve your overall wellbeing. CONNECT & GROW SUBSCRIBE for weekly evidence-based health content Get free resources: https://selfprinciple.org Follow Dr. Sean: @seanhashmimd MEDICAL DISCLAIMER This content is for informational purposes only and does not constitute medical advice. Always consult with your physician before making any decisions about your health or treatment. Do not delay seeking professional medical advice because of information presented here.