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Intraocularlens(IOL )Opacification is an uncommon but serious complication of cataract surgery. It can cause significant deterioration of visual performance and may necessitate IOL explantation. Clinical identification and evaluation of this condition is important as a misdiagnosis may prompt surgeons to perform unnecessary surgical procedures such as Nd YAG Capsulotomy and vitrectomy resulting in complications. Different patterns of opacification are observed in different IOL biomaterials such as Snowflake opacification in Polymethylmethacrylate (PMMA) IOLs, Discoloration in Silicone IOLs, Calcification in Hydrophilic acrylic IOLs and Glistenings in Hydrophobic acrylic IOLs. Differential diagnosis include Posterior capsular opacification, Vitreous haze or haemorrhage, Anterior lens epithelial cell proliferation, Inter lenticular Opacification in piggy back IOL. IOL exchange is the only therapeutic option in symptomatic patients with opacified IOL.IOL Exchange is associated with Zonular dehiscence(ZD), posterior capsular rupture(PCR) and corneal decompensation.The adherence of the deposits is extremely strong and Nd:YAG laser treatment is proven to be ineffective in the cleaning of the lenses' surfaces and unnecessary laser capsulotomy in eyes with opacified IOLs may also increase the complication rate during the IOL exchange procedure.