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Hemostasis represents a fundamental step in every surgical procedure. In particular, during neurosurgical procedures either cranial or spinal, a proper and robust hemostasis into confined spaces can greatly reduce the odds of peri-operative complications. Over the decades, multiple methods have been applied and several medical devices have been developed in order to promote and guarantee a proper hemostasis. Those different methods and hemostatic devices are usually grouped into three categories: mechanical, chemical and thermal. Among the various mechanical devices, bone wax and gelatin sponges are the main widely used hemostatic in neurosurgery with proven effectiveness. Over the years, several chemical, biological and combined hemostatic devices were further developed and proposed as valid alternative until today; fibrin sealants, oxidized cellulose, microfibrillar collagen, gel foam, Tranexamic acid and platelet-rich plasma have been proposed as novel ameliorating devices capable of promoting and ensuring a good hemostasis. Dr. Joe M Das is giving “Hemostatic Agents in Neurosurgery” lecture, don’t miss it!