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BREAKWATER Trial Explained | Targeted Therapy in Metastatic Colorectal Cancer (mCRC) In this video, we break down the latest clinical trial making headlines in the world of oncology — the BREAKWATER trial, focused on metastatic colorectal cancer (mCRC). Get a clear understanding of the trial design, treatment arms, outcomes, and what this means for the future of targeted therapy in colon cancer. Presented by Dr. Gunjan Desai, senior Gastrointestinal & HPB Surgeon at Lilavati Hospital, Mumbai, this video simplifies complex oncology data into clear, actionable insights — ideal for surgeons, oncologists, and students alike. 🧪 What You’ll Learn: 🔹 What is the BREAKWATER trial and why is it important? 🔹 Trial design: Phase III study overview 🔹 Role of encorafenib + cetuximab ± chemotherapy in BRAF V600E mutated mCRC 🔹 Patient selection and mutation profiling 🔹 Primary and secondary endpoints (PFS, OS, ORR, safety) 🔹 Interim results and clinical impact 🔹 How this trial compares with BEACON CRC and other targeted therapy data 🔹 What this means for personalized oncology in colorectal cancer 👨⚕️ Presented by Dr. Gunjan Desai Dr. Gunjan Desai is a highly respected GI and liver surgeon in Mumbai, with a special interest in GI oncology, surgical education, and evidence-based cancer care. He is also a DNB teaching faculty known for breaking down major trials for better understanding. 🎯 Best For: ✅ Surgical oncology and GI surgery residents ✅ Medical and radiation oncologists ✅ NEET SS and DNB aspirants ✅ Cancer researchers and pharmacologists ✅ Anyone tracking updates in colorectal cancer treatment 🔔 Like, Share & Subscribe for high-yield explanations of landmark GI and oncology trials! #BREAKWATERTrial #ColorectalCancer #TargetedTherapy #BRAFMutation #mCRC #DrGunjanDesai #GastrointestinalSurgeonMumbai #Cetuximab #Encorafenib #OncologyTrials #CancerResearch #DNBGeneralSurgery #NEETSSPrep #SurgicalOncology #LilavatiHospital #EvidenceBasedMedicine #GIOncology COME JOIN US: OUR DETAILS FACEBOOK: https://bit.ly/3qaO53R TWITTER: https://bit.ly/3legZw7 INSTAGRAM: https://bit.ly/33mAJaK E-MAIL ID: [email protected] WE SUPPORT AND RECOMMEND Freedom of expression, positivity, and meditation: https://rdbl.co/3fQMStK VISIT THE LINK, IF YOU DO TOO. OUR MOST VIEWED SURGERY VIDEOS STEP BY STEP LAPAROSCOPIC CHOLECYSTECTOMY: • Laparoscopic cholecystectomy - Step by ste... CRITICAL VIEW OF SAFETY IN LAP CHOLECYSTECTOMY: • Critical view of safety - What to do when ... So. let's have fun... Do SHARE, SUBSCRIBE, LIKE if you like the approach to this video. Also, LEAVE TOPICS, SUGGESTIONS in the comments. Let's make surgery fun, factual, and free...