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Amphetamine Psychosis

Amphetamine can cause psychosis. The psychosis fades quickly for some. But for others, it can persist for weeks or months, or longer. This lecture explores the mechanisms of amphetamine-related psychosis and the implications for treatment. 🙋🏽‍♀️ 🙋🏼‍♂️Want to send me a question? https://askapsychiatrist.info 📘 Chapters 📘 0:00 Amphetamine can cause psychosis 1:02 Chemical structure of amphetamine and derivatives 2:37 The difference between amphetamine and methamphetamine 3:36 MDMA (Ecstasy) links to amphetamine 4:25 What does amphetamine do? 5:47 The first amphetamine epidemic 6:52 The new amphetamine epidemic 8:10 Amphetamine can cause psychosis 9:06 The dopamine hypothesis of psychosis 10:32 Different patterns of amphetamine-related psychosis 12:10 Having an episode of substance-induced psychosis is linked to higher risk of later developing schizophrenia or bipolar disorder 13:32 Definition of substance-induced psychosis 15:33 Does amphetamine just ‘pull forward’ latent genetic risk? 16:55 Amphetamine-related persisting psychosis has a different pattern of medication response 18:00 Amphetamine-related persisting psychosis might involve free radical damage 19:57 Amphetamine can activate brain inflammation signals 20:56 Angiotensin receptors may be involved in amphetamine-induced inflammation signaling 21:43 Animal studies suggest benefits from angiotensin receptor blockers 22:23 Case reports of minocycline for amphetamine-induced psychosis 26:24 Risks associated with minocycline