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Complete the activity and claim your credit today: https://bit.ly/3J3XLuR Esophagogastric cancers, with 1.7 million new cases annually, are aggressive malignancies with poor prognoses. In Module 2 of this podcast, Dr. Yelena Y. Janjigian, Chief of the Gastrointestinal Oncology Service at Memorial Sloan Kettering Cancer Center, discusses strategies for optimizing treatment, including insights from recent trials like MATTERHORN and the role of biomarkers in tailored therapies. Stay informed on the latest advancements in esophagogastric cancer care to improve patient outcomes. Revisit Module 1 here: • Biomarker-Guided Strategies in Esophagogas... Follow us here: Facebook / i3health Instagram / i3health Linkedin / i3health Soundcloud / i3-health X / i3health STATEMENT OF NEED With an estimated 1.7 million new cases per year, esophagogastric cancers—consisting of cancers of the esophagus, stomach, and gastroesophageal junction (GEJ)—are an aggressive group of malignancies with a poor prognosis. The results of recent trials, including the MATTERHORN trial for resectable gastric and gastroesophageal junction adenocarcinoma, are rapidly improving outcomes in esophagogastric cancers, making it critical for the interdisciplinary care team to stay up to date on biomarkers and tailored treatment strategies (Li et al, 2023; Yu & Mehta, 2025; Janjigian et al, 2023). In Module 2 of this podcast, Yelena Y. Janjigian, MD, Chief of the Gastrointestinal Oncology Service at Memorial Sloan Kettering Cancer Center, will discuss strategies for optimizing treatment of esophagogastric cancer. DISCLOSURE OF RELEVANT FINANCIAL INFORMATION WITH INELIGIBLE COMPANIES i3 Health endorses the standards of the ACCME and ANCC that require everyone in a position to control the content of a CME/NCPD activity to disclose all financial relationships with ineligible companies that are related to the content of the CME/NCPD activity. CME/NCPD activities must be balanced, independent of commercial bias, and promote improvements or quality in healthcare. All recommendations involving clinical medicine must be based on evidence accepted within the medical profession. A conflict of interest is created when an individual has an opportunity to affect CME/NCPD content about products or services of an ineligible company with which he/she has a financial relationship, which therefore may bias their opinions and teaching. This may include receiving a salary, royalty, intellectual property rights, consulting fee, honoraria, stocks, or other financial benefits. i3 Health will identify, review, and mitigate all relevant financial relationships that speakers, authors, or planners disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. i3 Health does not endorse any products or services. Relevant financial relationships exist between the following individuals and ineligible companies: The i3 Health planners, reviewers, and managers have nothing to disclose. Yelena Y. Janjigian, MD, discloses that she has served on an advisory board or panel or as a consultant for AbbVie, Amerisource Bergen, Ask-Gene Pharma, Arcus Biosciences, Astellas, AstraZeneca, Basilea Pharmacutica, Bayer, BeOne, Boehringer Ingelheim, Bristol Myers Squibb, Daiichi Sankyo, Eisai, Eli Lilly, Geneos Therapeutics, Gilead Sciences, GlaxoSmithKline, Guardant Health, Health Advances, HMP Global, Imedex, Imugene, Inspirna, Lynx Health, Mashup Media, Master Clinician Alliance, Merck, Merck Serono, Mersana Therapeutics, PeerMD, Pfizer, Sanofi Genzyme, Seagen, Silverback Therapeutics, Suzhou Liangyihui Network Technology Co. Ltd., and Zymeworks; that she has received research funding from Astellas, AstraZeneca, Arcus Biosciences, Bayer, Bristol Myers Squibb, Cycle for Survival, Eli Lilly, Genentech/Roche, Inspirna, Merck, and Trascenta; and that she has is a stock/shareholder of Inspirna and Veda Life Sciences, Inc. i3 Health has mitigated all relevant financial relationships. #EsophagogastricCancer #CancerCare #OncologyEducation #MATTERHORNTrial #BiomarkerTesting #GastrointestinalOncology #TargetedTherapies #Immunotherapy #OncologyInnovation #PatientOutcomes