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Official Ninja Nerd Website: https://ninjanerd.org You can find the NOTES and ILLUSTRATIONS for this lecture on our website at: https://www.ninjanerd.org/lecture/sta... Ninja Nerds! In this microbiology lecture, Professor Zach Murphy provides a high-yield breakdown of the clinically important Staphylococcus species, focusing on Staphylococcus aureus, Staphylococcus epidermidis, and Staphylococcus saprophyticus. These Gram-positive cocci are major players in both community-acquired and healthcare-associated infections. We begin with an overview of the Staphylococcus genus, including its Gram stain appearance, catalase positivity, grape-like clusters, and facultative anaerobic metabolism. From there, we compare and contrast the key members of this group. The lecture dives deep into S. aureus, covering its coagulase positivity, protein A, and virulence factors like toxins and enzymes. We review its wide range of clinical presentations—from skin and soft tissue infections to endocarditis, osteomyelitis, toxic shock syndrome, and pneumonia—along with its association with methicillin resistance (MRSA). Staphylococcus epidermidis is discussed in the context of biofilm formation and prosthetic device infections, while Staphylococcus saprophyticus is highlighted as a common cause of urinary tract infections, particularly in young sexually active women. Enjoy the lecture and support us below! Table of Contents: 0:00 Lab 0:38 Staphylococcus Bacteria- Structure, Location, Characteristics 14:53 Pathophysiology of Staphylococcus Aureus 27:51 Pathophysiology of Staphylococcus Epidermidis 30:23 Pathophysiology of Staphylococcus Saprophyticus 34:13 Clinical Features of Staphylococcus Aureus 43:50 Clinical Features of Staphylococcus Epidermidis 47:02 Clinical Features of Staphylococcus Saprophyticus 47:57 Treatment of Staphylococcus Aureus Infection 55:14 Treatment of Staphylococcus Epidermidis Infection 58:02 Treatment of Staphylococcus Saprophyticus Infection 1:00:58 Comment, Like, SUBSCRIBE! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media / ninjanerdlectures / ninjanerdlectures / ninjanerdlectures https://x.com/ninjanerdsci/ / ninja-nerd 💬 Join Our Community Discord: / discord #ninjanerd #staph #microbiology