Autonomic Pharmacology | Adrenergic Antagonists скачать в хорошем качестве

Autonomic Pharmacology | Adrenergic Antagonists

Official Ninja Nerd Website: https://ninjanerd.org You can find the NOTES and ILLUSTRATIONS for this lecture on our website at: https://www.ninjanerd.org/lecture/aut... Ninja Nerds! In this high-yield pharmacology lecture, Professor Zach Murphy breaks down the essential concepts behind Adrenergic Antagonists, focusing on their mechanisms of action, receptor selectivity, clinical indications, and side effect profiles. This lecture will give you a structured understanding of how these drugs inhibit sympathetic nervous system activity and where they are used in clinical practice. We begin with a quick review of adrenergic receptor subtypes (α1, α2, β1, β2, β3) and their physiologic roles. From there, we categorize adrenergic antagonists based on their receptor specificity, including: • Alpha blockers: Prazosin, Doxazosin, Phenoxybenzamine, Phentolamine • Beta blockers: Propranolol, Metoprolol, Atenolol, Labetalol, Carvedilol, Esmolol, Timolol • Mixed alpha and beta blockers: Labetalol and Carvedilol • Selective vs non-selective agents Each agent is discussed in detail, highlighting: • Mechanism of action: Competitive antagonism at adrenergic receptors • Receptor selectivity: Impact on vascular tone, cardiac output, and bronchodilation • Clinical uses: Hypertension, angina, heart failure, arrhythmias, pheochromocytoma, glaucoma, BPH • Adverse effects: Bradycardia, bronchospasm, orthostatic hypotension, fatigue, rebound hypertension Enjoy the lecture and support us below! Table of Contents: 0:00 Lab 0:07 Adrenergic Antagonists Introduction 1:07 Adrenergic Neurons and Receptors 12:20 Adrenergic Target Organ Effects 24:47 Alpha 1 Antagonists 33:28 Alpha 1 + 2 Antagonists 49:48 Beta Antagonists 1:13:08 Beta 1 + 2 Antagonists 1:28:06 Beta + Alpha Blockers 1:40:30 Beta Blocker Overdose 1:47:30 Adrenergic Antagonists Practice Problems 1:58:54 Comment, Like, SUBSCRIBE! Pharmacology Source: Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition. Join this channel to get access to perks:    / @ninjanerdofficial   🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media   / ninjanerdlectures     / ninjanerdlectures     / ninjanerdlectures   https://x.com/ninjanerdsci/   / ninja-nerd   💬 Join Our Community Discord:   / discord   #ninjanerd #pharmacology #AdrenergicAntagonists