Pathological classification of restrictive cardiomyopathy; Obliterative and non obliterative скачать в хорошем качестве

Pathological classification of restrictive cardiomyopathy; Obliterative and non obliterative

Restrictive cardiomyopathy (RCM) can be pathologically classified into two main categories: Obliterative Restrictive Cardiomyopathy Characterized by: 1. Endomyocardial fibrosis: Scarring and fibrosis of the innermost layer of the heart muscle 2. Obliteration of the ventricular cavity: Scar tissue fills the ventricle, reducing its size and function 3. Often associated with: Hypereosinophilia (high levels of eosinophils in the blood) Tropical disease (e.g., endomyocardial fibrosis) Cancer (e.g., carcinoid heart disease) Non-Obliterative Restrictive Cardiomyopathy Characterized by: 1. Myocardial fibrosis: Scarring and stiffening of the heart muscle, without ventricular obliteration 2. Preserved ventricular cavity size 3. Often associated with: Amyloidosis (abnormal protein deposition) Sarcoidosis (inflammatory disease) Radiation therapy Genetic mutations (e.g., desmin, troponin) Note that some cases may exhibit features of both categories, and the classification may not always be clear-cut. Accurate diagnosis requires a combination of clinical, imaging, and histopathological evaluation. #Cardiomyopathy