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As we enter into the holiday season, many of us look forward to celebrating long-standing traditions with family and friends, which is no different from us here on the podcast! While not necessarily as long-standing as some of the other classic holiday traditions, after 2.5 years on air, we on this podcast have established our own end-of-year tradition, which is to take a look back at some of our favorite papers or more intriguing manuscripts published in the Journal of Clinical Microbiology over the past year. And so as you’ll see, thanks to the different areas of expertise and general interest among our panel today, we’ve selected quite a variety of papers to discuss, ranging from evaluation of new blood culture systems to use of metagenomics for infective endocarditis and to the potential application of interferon gamma release assays for detection of Histoplasma infections. And so, suffice it to say, there will be something of interest for everyone listening. But, for those watching today, you are clearly getting an extra special treat as you get to see us do this episode wearing our best holiday gear and accessories. This episode of Editors in Conversation is brought to you by the Journal of Clinical Microbiology and hosted by JCM Editor in Chief, Alex McAdam and Dr. Elli Theel. Visit https://journals.asm.org/journal/jcm to read articles and/or submit a manuscript. Follow EIC, Alex McAdam on twitter for JCM updates via / jclinmicro and co-host, Elli Theel at / ellitheelphd . Subscribe to the podcast at https://asm.org/eic Papers Reviewed: • https://doi.org/10.1128/jcm.00621-22 Pathogen Detection in Infective Endocarditis Using Targeted Metagenomics on Whole Blood and Plasma: a Prospective Pilot Study • https://doi.org/10.1128/jcm.00898-22 Fully Automated EUCAST Rapid Antimicrobial Susceptibility Testing (RAST) from Positive Blood Cultures: Diagnostic Accuracy and Implementation • https://doi.org/10.1128/jcm.03007-20 Stop Waiting for Tomorrow: Disk Diffusion Performed on Early Growth Is an Accurate Method for Antimicrobial Susceptibility Testing with Reduced Turnaround Time • https://journals.asm.org/doi/pdf/10.1... Detection of Newly Secreted Antibodies Predicts Nonrecurrence in Primary Clostridioides difficile Infection • https://journals.asm.org/doi/pdf/10.1... The Impact of Implementing the Virtuo Blood Culture System on the Characteristics and Management of Patients with Staphylococcus aureus Bacteremia • https://journals.asm.org/doi/pdf/10.1... Development of an Interferon-Gamma Release Assay (IGRA) to Aid Diagnosis of Histoplasmosis • https://journals.asm.org/doi/pdf/10.1... Accuracy of Tongue Swab Testing Using Xpert MTB-RIF Ultra for Tuberculosis Diagnosis • https://journals.asm.org/doi/pdf/10.1... Complementary Nonsputum Diagnostic Testing for Tuberculosis in People with HIV Using Oral Swab PCR and Urine Lipoarabionmannan DetectionHistoplasma 👍 Subscribe to ASM's YouTube channel at https://goo.gl/mOVHlK ✅ Become a member today at https://asm.org/Membership 🔬 Learn more about the American Society for Microbiology at https://www.asm.org 📱 Join us on social: Facebook: / asmfan Twitter: / asmicrobiology Instagram: / asmicrobiology