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Mastering Endovascular Techniques Chapter 78 Endovascular Treatment of Pulmonary Embolism This video serves as a comprehensive guide for medical professionals on endovascular interventions for treating acute pulmonary embolism (PE), a leading cause of cardiovascular death. The authors outline a shift from traditional anticoagulation toward catheter-directed therapies, which aim to rapidly reduce right ventricular strain by physically removing or dissolving life-threatening blood clots. Structured around a practical treatment algorithm, the source details the critical importance of risk stratification, highlighting that while anticoagulation prevents new clots, mechanical thrombectomy or local thrombolysis is often necessary for high-risk patients to prevent cardiac failure. Furthermore, the text provides an "endovascular toolkit" and specific technical protocols, emphasising that these procedures should be performed under monitored sedation rather than general anaesthesia to maintain haemodynamic stability. Ultimately, the purpose of the text is to define the roles of various aspiration and lytic devices within a multidisciplinary framework to optimise patient survival and prevent long-term complications like chronic pulmonary hypertension.