长期服用二甲双胍有哪些副作用 陈丹 湖北省中西医结合医院 скачать в хорошем качестве

长期服用二甲双胍有哪些副作用 陈丹 湖北省中西医结合医院

长期服用二甲双胍有哪些副作用 陈丹 湖北省中西医结合医院 二甲双胍是一种非常古老的药物，它有很好的降糖作用，属于临床的一线用药，它还具有抗肿瘤、防衰老的作用。但长期使用二甲双胍的有一定的副作用，包括胃肠道的一些反应，在使用的早期会出现腹痛、腹泻、纳差，如果长期使用，会让维生素B12缺乏，进而可能会导致患者末梢神经的功能改变，主要表现为四肢末端的麻木、疼痛等，所以长期使用二甲双胍的患者，需要监测维生素B12的浓度。 What are the side effects of taking metformin for a long time Metformin is a very old drug, It has a good hypoglycemic effect, It belongs to clinical first-line medication, It also has the function of anti-tumor and anti-aging. However, long-term use of metformin has some side effects, Including some gastrointestinal reactions, In the early stage of use, abdominal pain, diarrhea and poor appetite will appear, In case of long-term use, It makes vitamin B12 deficient, This may lead to changes in peripheral nerve function, It is mainly manifested in numbness and pain of the extremities, So people who use metformin for a long time, The concentration of vitamin B12 needs to be monitored.