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TIP: In summary, this process is very simply. You are drawing a specific amount of sterile water from one vial, and transferring it to the vial of freeze dried powder. *The powder / freeze dried bottle is vacuum sealed. Be sure to firmly hold the barrel and plunger of the syringe as you insert it into the rubber stopper of the freeze dried powder, as it may try to suck the water in very quickly. Control the speed at which the water is sucked into the vial and let the water in slowly. To mix a medication that is lyophilized powder (freeze-dried substance), carefully add the specified volume of reconstituting solvent (usually sterile water or a specific buffer) to the vial containing the powder, then gently swirl or rotate the vial to dissolve the powder completely, avoiding vigorous shaking which can damage the substance; always follow the specific instructions provided by the manufacturer for the correct solvent and mixing method. Key points to remember when mixing lyophilized powders: Check instructions: 1) Always consult the product information for the correct solvent volume and mixing technique. Your prescription will clearly specify how much water you are adding to the vial containing the freeze dried medication. 2) Gentle mixing: Use gentle swirling or rolling motions to dissolve the powder, avoiding vigorous shaking that could create bubbles or damage sensitive molecules. 3) Temperature control: Once mixed, refridgerate immediately. After mixing, visually inspect the solution for any undissolved particles or cloudiness, which may indicate improper reconstitution.