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Redistribution Pharmacokinetics

Explore our entire animation video library at: https://www.nonstopneuron.com/ All videos from general pharmacology: https://www.nonstopneuron.com/post/ge... Video Summary: In redistribution , drug is first distributed to one organ and then redistributed to other organ. It is typically seen with highly lipid soluble drugs. Such drugs are first distributed to organs with high blood supply and then gets redistributed to organs with less blood supply but are more bulky. If the site of action of drug is organ with high blood supply, redistribution leads to termination of action. For example general anesthesia induced by thiopentone disappears in few minutes due to redistribution. In this, initial distribution to brain due to high blood supply produces rapid anesthesia. But soon redistribution to muscles and fat which are more bulky, results in disappearance of anesthesia. 📽 More videos on Pharmacokinetics: • Rate of drug elimination in first order vs zero order kinetic:    • Rate of drug elimination in first order vs...   • First Order Elimination Kinetic:    • You Will NEVER GET CONFUSED Regarding Firs...   • Zero Order Elimination Kinetic:    • UNSUBSCRIBE ME IF You Don't Understand Zer...   • Mixed Order Kinetic:    • NOBODY EXPLAINED Mixed order kinetic (Satu...   • Plasma Half Life:    • Plasma Half Life || Elimination Half Life   • Terminal Half Life:    • Terminal Half Life   • Clearance definition explained:    • Clearance definition explained   • Apparent Volume of Distribution:    • Apparent Volume of Distribution   ● Follow me at: • Facebook:   / nonstopneuron   • Instagram:   / nonstopneuron   #NonstopPharmacokinetics DISCLAIMER: This video is for education purpose only. Although every effort is made to ensure accuracy of material, viewer should refer to the appropriate regulatory body/authorized websites, guidelines and other suitable sources of information as deemed relevant and applicable. In view of possibility of human error or changes in medical science, any person or organization involved in preparation of this work accepts no responsibility for any errors or omissions or results obtained from use of information in this video.