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Ithmid kohl (a.k.a. kajal or surma) have been used for thousands of years as eyeliner for the eye. But it isn’t only for aesthetics. Ithmid kohl has been used in the past medicinally to treat eye related ailments, and the benefits are even shown in some scientific studies. Note that Ithmid kohl refers to the pure powdered mineral of Galena, which is essentially lead sulfide. So what are the benefits of Ithmid kohl? Well firstly, it provides protection against ultraviolet (UV) radiation from the sun. The Galena that the kohl is made out of has UV absorptive properties, so when the user applies the powderized galena kohl to the eyes the microscopic particles of galena form a thin film over the eye and absorbs the incoming UV rays from the sun. And given that galena is dark grey & shiny, it also helps reflect off the bright glare from the sun. Consider that black or dark colored objects have nearly all the light touching it absorbed by its surface, so that nearly none is reflected back to your eye. That’s why it looks opaque to you. The reason why its important that ithmid kohl absorbs the UV rays is because excessive exposure of sunlight to the eyes is a risk factor for macular degeneration. Macular degeneration refers to the back of the eye deteriorating, which is where the retina is connected to the eye. This causes the center of one’s vision to blur or be totally lost. The secondary main benefit of Ithmid kohl is that it promotes the production of Nitric Oxide in the eye. Raising the level of Nitric Oxide (NO) has a wide range of benefits, one of which is improving the immune system’s ability to fight infections. The process by which NO levels are raised starts with the lead sulfide’s Pb2 + ions stimulating keratinocytes (cells that make up the outermost layer of the eye, like the cornea) to undergo an oxidative stress response, which includes the overproduction of nitric oxide. Nitric Oxide (NO) itself cannot be used as a drug, because it quickly breaks down in a few seconds. So finds ways to stimulate the body’s own production of NO is better.