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Hepatitis B serologies

This is a short video describing three serologic markers for Hepatitis B and how they can be used to describe a persons Hep B infection status. I created this presentation with Google Slides. Image were created or taken from Wikimedia Commons I created this video with the YouTube Video Editor. ADDITIONAL TAGS: remote infx (cleared) inactive chron. carrier acute infx Hepatitis B serologies Marker Meaning Acute infection Window period Chronic infection Remote infection (cleared) Immun- ization Inactive chronic carrier HBcAb Exposure + + + + - + HBsAg Infection + - + - - - HBsAb Immunity - - - + + - Time after exposure Titer window per. The easiest way to remember the signfiicance of each of these serologic markers is with the words in teh second column. HBcAb indicates that a patient has been EXPOSED to hepatitis B. HBsAg indicates that a patient has been INFECTED with Hep B. And HBsAb indicates that a person is IMMUNE to HepB. So, using these three terms, it’s easy to fill out the rest of the chart. In an acute infection, a person has been exposed (that’s how they got infected) and they’re obviously infected. They are not immune -- they still have the infection. This actue infection phase is indicated in the table below.. The person just got infected, and the body responds by making the core Ab that it will keep forever, and there is still viral antigen around . Next is the window period, which is after the