4. Necroptosis And Pyroptosis : USMLE Step 1 скачать в хорошем качестве

4. Necroptosis And Pyroptosis : USMLE Step 1

📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:-   / drgbhanuprakash   📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr 📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash Necroptosis and Pyroptosis Necroptosis and Pyroptosis are two forms of programmed cell death that differ from the traditional apoptosis pathway, playing significant roles in the body's defense mechanisms against infections and in inflammatory responses. Necroptosis is a type of cell death that mimics necrosis but is regulated by specific signaling pathways. Triggered by factors like TNF-alpha, it involves the formation of a complex including RIPK1, RIPK3, and MLKL proteins, leading to cell membrane rupture and release of cell contents, often triggering inflammation. Pyroptosis, on the other hand, is an inflammatory form of programmed cell death primarily triggered by infections. It is characterized by the activation of caspase-1 or caspase-11 in mice (caspase-4 and caspase-5 in humans), which leads to the cleavage of gasdermin D, forming pores in the cell membrane and causing cell lysis. Pyroptosis plays a crucial role in the immune response by eliminating infected cells and releasing inflammatory signals to recruit immune cells. Necroptosis: _____________ Regulated necrosis-like cell death Involves RIPK1, RIPK3, and MLKL proteins Leads to inflammation through membrane rupture Triggered by factors like TNF-alpha Pyroptosis: ___________ Inflammatory form of programmed cell death Triggered by infections Involves caspase-1, caspase-4, caspase-5, and gasdermin D Results in cell lysis and release of inflammatory signals Both necroptosis and pyroptosis highlight the body's intricate methods for controlling cell fate in response to stress and infection, emphasizing their roles in immunity and inflammation. #Necroptosis #Pyroptosis #CellDeath #Inflammation #Immunology #MBBS #MedicalStudents #BoardExamPrep #InfectiousDiseases #FutureDoctors #MedScience #fmge #fmgevideos #rapidrevisionfmge #fmgejan2023 #mbbslectures #nationalexitexam #nationalexittest #neetpg #usmlepreparation #usmlestep1 #fmge #usmle #drgbhanuprakash #medicalstudents #medicalstudent #medicalcollege #neetpg2023 #usmleprep #usmlevideos #usmlestep1videos #medicalstudents #neetpgvideos #pathologyvideos #usmlepathology