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Maximizing RIRS Outcomes: Tilt for Enhanced Stone Removal and Optimizing Surgeon’s Ergonomics Layman Abstract : Retrograde Intrarenal Surgery (RIRS) is a modern, minimally invasive technique used to treat kidney stones. It has improved significantly over older methods like shock wave therapy (ESWL), thanks to advances in laser technology and flexible surgical tools. This chapter provides an in-depth look at RIRS, focusing on a new approach called Tilted RIRS (T-RIRS), which helps make stone removal easier by adjusting the patient’s position based on stone location. It also discusses different ways to break stones, new surgical tools, and ways to improve surgeon comfort and efficiency. RIRS is now a widely accepted method for treating kidney stones up to 1.5 cm in size, offering excellent results with minimal discomfort. With ongoing advancements in artificial intelligence, imaging, and personalized treatments, the future of kidney stone treatment looks even more promising. ---------- Original Abstract : Introduction: Retrograde intrarenal surgery (RIRS) has emerged as a transformative minimally invasive approach in the management of intrarenal calculi. The evolution from traditional methods like Extracorporeal Shock Wave Lithotripsy (ESWL) to RIRS represents a significant advancement in urological practice, particularly with the integration of advanced laser technology and flexible ureteroscopes. Aim: This chapter aims to provide a comprehensive overview of RIRS, examining its technical aspects, and recent innovations, particularly the Tilted RIRS (T-RIRS) technique, and addressing the challenges and future directions in the field. Results: The chapter presents detailed insights into patient positioning techniques, including the novel T-RIRS approach, which optimizes stone accessibility through specific table tilts based on stone location. It explores stone fragmentation methods (dusting and fragmentation), navigation techniques, and technological innovations such as advanced laser systems and disposable ureteroscopes. The review also addresses crucial aspects of surgeon ergonomics and complication management, supported by current literature and clinical evidence. Conclusion: RIRS has established itself as a standard of care in treating lower pole renal calculi for sizes up to 1.5 cm, offering excellent outcomes while maintaining minimal invasiveness. The introduction of T-RIRS and other technological advancements continues to enhance procedural efficiency and surgeon comfort. Future developments in artificial intelligence, imaging techniques, and personalized treatment approaches promise to further revolutionize this field. View Book: https://doi.org/10.9734/bpi/mono/978-... #Retrograde_intrarenal_surgery #T_RIRS #urolithiasis #stone_fragmentation #minimally_invasive_surgery