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#23118

Presence of JC polyomavirus (JCPyV) in the Urinary Tracts of Women with UTI-like Symptoms Mormando R1, Wolfe A1, Putonti C1 1. Loyola University Chicago KEYWORDS: Basic Science, Infection, Urinary Tract, Molecular Biology The JC polyomavirus (JCPyV) is most commonly found within the urinary tract, and prior studies estimate that this virus persists within the kidneys of 20-60% of older adults [1]. To date, only two shotgun metagenomic sequencing studies have been conducted of the urinary viral community (urinary virome or urovirome) of individuals with UTI symptoms (N=54) [2,3]. Both studies reported the presence of JCPyV in the urovirome of these individuals, but JCPyV has not been previously associated with UTI symptoms. This prompted our investigation into the prevalence of JCPyV in women with UTI-like symptoms.