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Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this embryology lecture, Professor Zach Murphy covers the early stages of human development, including fertilization, cleavage, and blastulation. This lecture sets the foundation for understanding how a single cell becomes a multicellular embryo ready for implantation. We begin with fertilization, detailing the sperm's journey, the processes of capacitation and the acrosomal reaction, and how the sperm penetrates the zona pellucida to fuse with the oocyte. Zach explains how polyspermy is prevented, how the zygote is formed, and how this event restores diploidy and initiates embryogenesis. The lecture then transitions into cleavage, the series of rapid mitotic divisions that transform the zygote into a multicellular structure. You’ll learn how cells called blastomeres form, how compaction occurs, and the development of the morula as the embryo moves through the uterine tube. Finally, we cover blastulation, where fluid accumulation creates a blastocyst cavity, dividing the embryo into the trophoblast and inner cell mass. Zach breaks down how the blastocyst prepares for implantation and sets the stage for gastrulation and germ layer formation. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media / ninjanerdlectures / ninjanerdlectures / ninjanerdlectures https://x.com/ninjanerdsci/ / ninja-nerd 💬 Join Our Community Discord: / discord #ninjanerd #FertilizationCleavageBlastulation #Embryology