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Broadcast from KSQD on 5-30-2024 and replayed on 2-12-2026: • Cognitive errors in medicine dismissing unusual presentations as psychological. • A case of Pediatric Autoimmune Neuropsychiatric disorders Associated with Streptococcal Infections (PANDAS). • Anti-NMDA receptor encephalitis causing psychiatric symptoms. • Failures of genetic research to identify causes. • The Need for integrating neurology and psychiatry; Importance of testing for antibodies and using MRI scans. • Detailed explanation of immune tolerance, peripheral tolerance, and the phenomenon of molecular mimicry in diseases like multiple sclerosis and celiac disease. • Importance of addressing root causes rather than just symptoms. • Historical context and current advancements in treating autoimmune diseases like type 1 diabetes, lupus, and multiple sclerosis using reprogrammed immune cells and iron oxide nanoparticles. • Explanation of how the liver filters blood and helps establish immune tolerance by processing cellular debris and antigens. • Advances in engineering regulatory T cells to target specific disease sites and calm inflammatory responses. • Exploration of new diagnostic tools and the potential of AI in understanding complex psychiatric conditions.