The Genius of Genetics: Gene Therapy, Synthetic Organisms, and beyond! скачать в хорошем качестве

The Genius of Genetics: Gene Therapy, Synthetic Organisms, and beyond!

Ira Pastor ideaXme longevity and aging ambassador interviews George Church, Professor Harvard Medical Centre and MIT, founder Personal Genomes and co-founder of eGenesis and Editas. Ira Pastor comments: Today, as we continue our journey through the bio-architecture of the health aging process, we are going to take some time to hang out at the level of the genome, as well as at the level of the respective bio-products, both natural and "non-natural" that peel off of this genomic knowledge base, not just only for the purposes of human health, but for also for agriculture, energy, the environment, as well some very novel possibilities which for now we will classify as “other”. A lot has changed since we first mapped the human genome back in 2003. But as time has moved on, we have learned so much more in terms of the complexity and uniqueness of this “genomic space”. We’ve discovered that the genome is fluid and highly networked; filled with endless feedback loops, hierarchies of control. We've leant that it contains intricate phenomena such as epistasis, pleiotropy, alternative splicing; it has an endless array of architecture based on all of its non-coding space; and the human genome is continually interacting with its environments, metabolic architecture of the cell, other cells, individuals, species, yielding variations in traits. It’s truly a fascinating area, and one that we can leverage for so much possibility as far as human enhancement is concerned in the future. No-one better to join us in a discussion about these topics is our guest Professor George Church, the thought leader of all thought leaders in the genetics, synthetic biology space. Dr. Church in is a geneticist, molecular engineer, and chemist. He is the Robert Winthrop Professor of Genetics at Harvard Medical School, Professor of Health Sciences and Technology at Harvard and MIT, and was a founding member of the Wyss Institute for Biologically Inspired Engineering at Harvard. His 1984 Harvard PhD included the first direct genome sequencing, molecular multiplexing & DNA barcoding which eventually lead to the first complete genome sequence published of Helicobacter pylori. He helped initiate the Human Genome Project in 1984 and the Personal Genome Project in 2005, which today provides the world's only open-access human genome & trait database His innovations in "next generation" genome sequencing and synthesis and cell, tissue engineering which resulted in over a dozen companies including those involved in medical genomics, synthetic biology, gene therapy and full human genome sequencing, as well as new privacy, biosafety & biosecurity policies. He is also Director of the U.S. Department of Energy Technology Center and Director of the National Institutes of Health Center of Excellence in Genomic Science. He has received numerous awards including the 2011 Bower Award and Prize for Achievement in Science from the Franklin Institute and election to the National Academy of Sciences and Engineering. He’s author of hundreds of peer publications, patents, and a wonderful book called Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves which comes with a tag line on Amazon “A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. On the show Professor Church talks to me about: His background, how he got interested in science, in genetics, and how he finds himself at the epicenter of the translational biosciences space in 2019. His exceptional amount of technology transfer linked biotech startup activities He reveals his genetic approaches to aging and the diseases of aging, which use combinatorial gene therapy strategies. He talks of his activities in the world of synthetic biology. He explains his thoughts on the colonization of space, as well as the de-extinction of mammoths, dinosaurs, and neanderthals. For all the links supporting this interview visit www.radioideaxme.com ideaXme is a podcast, ambassador and mentor programme. Mission: Move the human story forward! Find us on multiple platforms including iTunes, SoundCloud, Spotify, Radio Public, I Heart Radio and www.radioideaxme.com.. Follow us on twitter @ideaxm @IraSamuelPastor @geochurch