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This is a thank you video to Morris Animal Foundation donors from Greta Benedetti, a veterinary student at the University of Perugia, Italy. She recently received a Veterinary Student Scholars grant from the Foundation for her animal health research project, Macrophage Response in the Prognostic Evaluation of Feline Meningioma. In the cat, the most common neurological signs associated with meningioma are change of behaviour, lethargy, circling, and seizures, followed by disorientation, incoordination, anorexia, blindness. Although meningioma of the cat is most commonly of low grade, recurrence is reported in about 30% of cases at a median range of 28 months. Therefore, the prognostic evaluation represents the key point in the health care of an oncologic patient. Although a number of factors can influence the individual outcome during the oncologic disease, it is absolutely necessary to come close as much as possible to the evaluation of the biological behaviour of the tumour. A number of important repercussions and socioeconomic impacts related to the proposed project are reported: To improve the ethical approach to the oncologic patient makes the owner much more aware about survival time, tumour recurrence and post-surgery quality of life. The latter, when bad, assumes consistent socioeconomical implications and One Health guise resulting in significant financial and psychological discomforts on people living with oncologic pets. A much more mature awareness in front of the biological behaviour of tumour from both the owner and clinician is an essential added social value in the whole management of oncologic cases. To investigate the relationship between macrophage cell subtype and prognosis can add further elements to the prognosis evaluation of the feline meningioma by neurologist and increase the owner’s aware about the animal health in term of postsurgery clinical outcome and quality of life of pets. This study can also open new perspectives aimed to define novel therapeutic strategies contributing to improve animal health.