MALDI-MS for Visualizing Amyloid Deposits in the Brain | Protocol Preview скачать в хорошем качестве

MALDI-MS for Visualizing Amyloid Deposits in the Brain | Protocol Preview

Watch the Full Video at https://www.jove.com/v/57645/visualiz.... Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry - a 2 minute Preview of the Experimental Protocol Masaya Ikegawa, Takashi Nirasawa, Nobuto Kakuda, Tomohiro Miyasaka, Yuki Kuzuhara, Shigeo Murayama, Yasuo Ihara Doshisha University, Department of Life and Medical Systems; Bruker Daltonics K.K.,; Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, The Brain Bank for Aging Research; Doshisha University, Graduate School of Brain Science; Molecular imaging with matrix-assisted laser desorption/ionization-based imaging mass spectrometry (MALDI-IMS) allows the simultaneous mapping of multiple analytes in biological samples. Here, we present a protocol for the detection and visualization of amyloid β protein on brain tissues of Alzheimer's disease and cerebral amyloid angiopathy samples using MALDI-IMS. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel:    / jovejournalofvisualizedexperiments