Electrochemical Biomarker Detection in Common Metabolic Disorders скачать в хорошем качестве

Electrochemical Biomarker Detection in Common Metabolic Disorders

Electrochemical detection is an umbrella term for many different methods. It uses chemical reactions or mechanisms on a sensor to create electrons or influences the flow of electrons. This is proportional to the concentration of biomarker of interest and can then be measured and quantified using a chip. CBmeds research interest lies in applied science, this means bringing the research result to the patients to improve care and cure. One of the big advantages is that electrochemical measurement can be made simple. If done right, we get a device like the glucose measurement which can be performed by everyone. Metabolic control is of utmost importance for a number of common metabolic diseases, such as diabetes and insulin resistance. Parameters like fasting glucose in blood are difficult to obtain and only a short-cut in overall disease monitoring, HbA1c a sometimes too long-lasting tool. By using a new electrochemical biomarker approach via urinary parameters, an easy-to-measure C-peptide value in urine might be a potential diagnostic and monitoring tool for underlying diseases such as diabetes or other metabolic disorders. Potential other biomarkers for various diseases might be established via this chip technology in future. A new electrochemical chip-based technology for analytical detection and validate potential biomarkers for common metabolic disorders is planned to be established. The scientific knowledge of the Endocrinology Lab Platform and patients / samples from the Graz cohorts as well as prospective clinical study samples can be used for the development of chip-based diagnostics. In close cooperation with our industry partners, CBmed focusses on the identification, testing and validation of biomarkers using the appropriate equipment of the CBmed consortium as well as continuous deep clinical phenotyping and extensive biobanking. In this video, CBmed experts Sharmaine Reintar and Christoph Haudum give insights in their latest scientific approach.