CASCADE FH Disparities in Familial Hypercholesterolemia (FH) скачать в хорошем качестве

CASCADE FH Disparities in Familial Hypercholesterolemia (FH)

Joshua Knowles, Chief Medical Advisor, FH Foundation presents data from the CASCADE FH Registry at the FH Global Summit that highlights potential health disparities that contribute to the undertreatment of individuals with familial hypercholesterolemia (FH). Despite 50+ years of research in patients with familial hypercholesterolemia (FH), few prior studies have evaluated health disparities across multi-ethnic cohorts. After analyzing data from more than 3,000 U.S. adults in the CASCADE FH Registry, the investigators found that women were more undertreated than men, and Asians and Blacks were more undertreated than Whites. First presented at the 2017 FH Global Summit and then published in the journal Atherosclerosis. Individuals with FH are already underdiagnosed and undertreated, even though they are at high risk for cardiovascular disease. An estimated 1 in 250 Americans have FH, but 90% of those are undiagnosed. FH is the most common dominantly inherited genetic disorder. FH causes high LDL-C, or bad cholesterol, from birth. Left untreated, men with FH have a 50% risk for a fatal or nonfatal coronary event by age 50 and women have a 30% risk by age 60.