The First Stem Cell Model of PTSD: What It Means For Research and Treatment скачать в хорошем качестве

The First Stem Cell Model of PTSD: What It Means For Research and Treatment

How are stem cells changing our understanding of PTSD?​​ Post-traumatic stress disorder (PTSD) is a psychiatric disorder that may occur after experiencing a traumatic event, but only for a minority of people. Understanding why certain individuals are susceptible to PTSD has been a challenge, as scientists lacked the means to capture how the neurons of prone individuals are affected by stress. A new study by NYSCF scientists and collaborators reveals unique features of the PTSD brain by creating the first-ever stem cell model of the disorder from a cohort of 39 combat veterans and healthy controls. Hear from experts Kristin Brennand, PhD (Yale University), Daniel Paull, PhD (The NYSCF Research Institute), and Rachel Yehuda, PhD (Icahn School of Medicine at Mount Sinai and Office of Veterans Affairs) about their latest study that created the first-ever stem cell model of PTSD, and discovers new features of the disease that could be targeted therapeutically. The discussion will open with remarks by NYSCF’s interim CEO Derrick Rossi, PhD, and will be moderated by our Vice President of Scientific Outreach, Raeka Aiyar, PhD. What you’ll learn: – How stem cells can help us understand why some people get PTSD and others don’t – How NYSCF’s stem cell technologies are making large-scale studies of PTSD possible – What these newly discovered disease signatures mean for the future of treatments 00:00 Introduction 05:20 What is PTSD? How did the study come about? 12:56 What do we know about the genetics of PTSD? 17:12 Why was NYSCF’s robotic technology critical for this study? 22:40 What were the main findings of the study? 34:52 How do different people respond to trauma? 37:15 What was unique about this patient cohort? 41:37 What was unique about PTSD-affected neurons? 48:15 What gender and racial disparities exist in PTSD? 51:10 How can genetics inform future PTSD treatments? 55:29 Could psychedelics be used to treat PTSD? 58:08 What makes you hopeful about the future of PTSD research and treatments? #ptsdrecovery #genetics #posttraumaticstressdisorder