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Diane K. Newman, DNP, ANP-BC, FAAN, FAUNA, BCB-PMD, Adjunct Professor of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, introduces Jill Peters-Gee, MD, Retired Urologist, Author, Support Group Facilitator for IC/BPS, West Hartford, Connecticut. In this 12-minute presentation, Dr. Peters-Gee presents a comprehensive overview of interstitial cystitis (IC), focusing on phenotyping as a diagnostic and therapeutic strategy. The complexity of IC lies in its heterogeneity, necessitating a personalized approach rather than one-size-fits-all treatments. Dr. Peters-Gee introduces a framework based on phenotypes to address this, expanding upon existing AUA guidelines that outline ulcerative, bladder-centric, myofascial, and central sensitization types. She builds on this by presenting seven phenotypes: ulcerative IC, urethral, infection-based, general bladder, myofascial, neuralgia-related, and central sensitization. These categories are informed by current research and her clinical experience, offering a more nuanced view of symptom origin. Her approach guides diagnosis and treatment, enabling more precise management based on symptom clusters and underlying mechanisms. Dr. Peters-Gee discusses her book IC: Journey to Wellness, a resource for patients and healthcare providers. It includes tools for identifying phenotypes, understanding associated conditions, and implementing tailored therapies. Additional resources, including support groups and patient tools, are available on her website, icjourneytowellness.com. The presentation includes a short question-and-answer conversation between Dr. Peters-Gee and Diane Newman. Don't forget to join the GRU Community: https://grandroundsinurology.com/regi... Follow us on Twitter/X: https://x.com/GRUrology And like and subscribe to us here on YouTube!