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Mitochondria control of physiology and disease: beyond ATP

Mitochondria control of physiology and disease: beyond ATP Air date: Wednesday, March 7, 2018, 3:00:00 PM Category: WALS - Wednesday Afternoon Lectures Runtime: 00:57:53 Description: NIH Director’s Wednesday Afternoon Lecture Series Historically, mitochondria have been primarily viewed as biosynthetic and bioenergetic organelles that generate metabolites for the production of macromolecules and adenosine triphosphate (ATP), respectively. The work of the Chandel laboratory has elucidated that mitochondria have a third distinct role whereby they release reactive oxygen species (ROS) and metabolites to regulate transcription factors and epigenetics. For his lecture, Dr. Chandel will present his lab’s ongoing efforts to understand how mitochondria, in addition to producing ATP, regulate cancer and immunity. For more information go to https://oir.nih.gov/wals/2017-2018 Author: Navdeep S. Chandel, Ph.D., David W. Cugell Professor of Medicine, Northwestern University Permanent link: https://videocast.nih.gov/launch.asp?...