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How can a single molecule affect your heart, eyes, and brain all at once...in both a good way and a bad way? This video zooms into the inner workings of belladonna's mortal medicine. ▫️ written by Roshni, narrated & edited by April ▫️ check out Patrick Kelly's video to learn more about the history of this compound • How This Poisonous Plant Became Medicine (... ▫️ read more: http://www.metabolic-pathway.com/full... https://en.wikipedia.org/wiki/Pigeonh... ▫️ sources: +Maurya, V. K., et al. (2020). Dark Classics in Chemical Neuroscience:An Evidence-Based Systematic Review of Belladonna. ACS Chemical Neuroscience. https://doi.org/10.1021/acschemneuro.... +ChEMBL Tree, from PubChem Classification Browser, NIH https://pubchem.ncbi.nlm.nih.gov/clas... Anjali Jaiman & Mukund Thattai (2020). Golgi compartments enable controlled biomolecular assembly using promiscuous enzymes. eLife https://doi.org/10.7554/eLife.49573 ▫️ image & footage credit: neuron video: NIH [flickr] https://www.flickr.com/photos/nihgov/... nicotinic receptor: [PDB] https://www.rcsb.org/3d-view/ngl/6uwz muscarinic receptor: [PDB] https://www.rcsb.org/structure/3uon cat pupil video: lizcat [YouTube] • Minnie’s “Murder” Eyes poison psa: 'Poison' by John Ralmon retrieved from A/V Geeks [YouTube] • Danger - Poison 'Health Hazards of Pesticides' retrieved from A/V Geeks [YouTube] • Health Hazards of Pesticides Funded by: UPMC Hillman Academy & NCI R25 YES #science #chemistry #poison Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Science Foundation, National Institutes of Health or UPMC.