Hyperinsulinism: Ben's Story скачать в хорошем качестве

Hyperinsulinism: Ben's Story

For decades, Children’s Hospital of Philadelphia has been on the forefront of treating hyperinsulinism. http://www.chop.edu/hyperinsulinism See how that expertise benefited Ben, who has been a patient for 23 years. When doctors at the hospital where Ben was born didn’t know how to manage his congenital hyperinsulinism (HI), his family brought him to CHOP. There, doctors determined he needed to have most of his pancreas removed. When a baby has HI, the beta cells in their pancreas release way too much insulin, which lowers their blood sugar to dangerous levels. Severe low blood sugar can cause seizures and, potentially, brain damage or even death. That’s why it’s essential to raise sugar levels to the normal range, and keep them there. Sugar is also necessary for brain growth and development. CHOP’s Surgeon-in-Chief N. Scott Adzick, who has performed more pancreatectomies than any other surgeon —500-plus — operated. Because Ben had a serve form of diffuse HI, he still needed medication to keep his blood sugar at a safe level. In his teens, he developed diabetes. Through it all, he was cared for by the multidisciplinary team that makes up CHOP’s Congenital Hyperinsulinism Center, the most active center in the world. HI is rare, with only one case in 50,000 births, but CHOP’s unparalleled experience treating these children means patients receive the best, most advanced care available. The center is directed by pediatric endocrinologist Diva De León-Crutchlow, MD, MSCE. Researchers at Children’s Hospital are actively exploring ways to improve treatment for all types of HI. Their work has led to breakthroughs in treatment. For example, for children who have a form of the disease called focal hyperinsulinism, where only a part of their pancreas is involved, CHOP pioneered a special PET scan that helps identify the diseased part. These babies can often be cured through surgery. Since CHOP’s HI Center opened 20 years ago, more than 240 children have been cured.