Using Stem Cells to Mimic the Amniotic Sac скачать в хорошем качестве

Using Stem Cells to Mimic the Amniotic Sac

Researchers haven’t been able to study the amniotic sac in detail because it forms alongside developing embryos. In pregnancy, the inside of the womb is inaccessible to scientists, and human embryos in the lab can’t be studied after 14 days for ethical reasons. Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, (post gastrulation amnioids or PGAs), which replicates development of the tissues supporting the embryo from two to four weeks after fertilisation. This is the first model of amniotic sac development after two weeks. In this video, Crick scientists Silvia Santos and Borzo Gharibi explain why these models could be so important. The new model can be used to study the origin and function of the human amnion and help identify previously unknown ways the amniotic sac might support embryonic development. This model could also help researchers explore complications involving the amniotic sac, such as fluid imbalance, Amniotic Band Syndrome (ABS), and premature rupture of membranes. These conditions can lead to serious outcomes like fetal malformations, growth restriction, or preterm birth, and understanding their origins may guide future medical advances. It also holds promise for potential use in medical procedures that make use of the amniotic membrane. Visit our website to find out more about the study: https://www.crick.ac.uk/news/2025-05-... #amnioticsac #stemcells #science In this video 00:00 Intro 00:38 Mysteries of the Amniotic Sac 01:10 Making PGAs 02:13 Studying PGA Development 03:26 Interactions With Embryonic Stem Cells 03:55 Potential Applications 04:35 Conclusion The Francis Crick Institute The Francis Crick Institute is a biomedical research institute and independent charity. We bring together people from different fields and specialisms to tackle some of the biggest questions in health and disease. Based in the heart of London’s Kings Cross, we’re the biggest biomedical research facility under a single roof in Europe and are home to a free public exhibition space. Keep up to date with everything going on at the Crick • https://www.crick.ac.uk • https://bsky.app/profile/crick.ac.uk •   / the-francis-crick-institute   •   / thefranciscrickinstitute   •   / thecrick   •   / thefranciscrickinstitute