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📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr 📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- / drgbhanuprakash 📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash Parathyroid Glands Gross Anatomy (Animation): Blood supply & Nerve supply, Histology & Development - ------------------------------------------------------------------------------------------------------------------ The parathyroid glands are small endocrine glands located on the posterior surface of the thyroid gland, typically numbering four, but variations exist. These glands play a critical role in regulating calcium homeostasis within the body through the secretion of parathyroid hormone (PTH). This hormone is essential for increasing blood calcium levels by promoting calcium release from bones, increasing renal tubular reabsorption of calcium, and stimulating the production of active vitamin D in the kidneys. Understanding the gross anatomy, blood supply, nerve supply, histology, and development of the parathyroid glands is crucial for comprehending their function and the implications of parathyroid disorders. 🌟🩺 1. Gross Anatomy and Location 📍 The parathyroid glands are usually located on the posterior aspect of the thyroid gland. They are situated within the thyroid capsule, typically two glands on each side, and can vary in size and position. Each gland is approximately the size of a pea, weighing around 30-40 mg. Their proximity to the thyroid gland is important for surgical considerations, particularly during thyroidectomy, where there is a risk of damaging these vital glands. 2. Blood Supply and Nerve Supply 🩸⚡ Blood Supply: The primary blood supply to the parathyroid glands is derived from the inferior thyroid arteries, which branch off from the subclavian artery. The superior thyroid arteries may also provide additional blood flow. This rich vascular supply is essential for delivering hormones directly into the bloodstream and supporting the metabolic activity of the glands. Nerve Supply: The parathyroid glands receive autonomic innervation from the sympathetic nerves that originate from the cervical sympathetic ganglia. However, the precise role of this innervation in regulating parathyroid function is still a subject of research. 🧠 3. Histology: Cellular Composition and Function 🔬 Histologically, the parathyroid glands are composed primarily of two types of cells: Chief Cells: These are the predominant cells, responsible for synthesizing and secreting parathyroid hormone (PTH). They appear small and have a basophilic cytoplasm due to the presence of rough endoplasmic reticulum and Golgi apparatus, which are involved in protein synthesis. Oxyphil Cells: These cells are larger and less numerous. Their function is not entirely understood, but they may play a role in the regulation of calcium levels and are thought to increase in number with age. They are characterized by their eosinophilic cytoplasm and are believed to have a role in the metabolic processes of the gland. 4. Development: Embryological Origin 🌱 The parathyroid glands develop from the third and fourth pharyngeal pouches during embryogenesis. The inferior parathyroid glands arise from the third pouch, while the superior parathyroid glands originate from the fourth pouch. This embryological origin explains the variation in position that can occur in some individuals. The glands migrate as the fetus develops, which can sometimes lead to ectopic parathyroid tissue being found in locations such as the thymus or near the carotid arteries. #ParathyroidGlands #Endocrinology #MedicalEducation #CalciumHomeostasis #Histology #Anatomy #BloodSupply #NerveSupply #Embryology #MedStudentLife #SurgicalAnatomy #ThyroidHealth #HormonalRegulation #HealthcareEducation #medicalanimations #fmge #fmgevideos #rapidrevisionfmge #fmge2024 #mbbslectures #nationalexitexam #nationalexittest #neetpg #usmlepreparation #usmlestep1 #fmge #usmle #drgbhanuprakash #medicalstudents #medicalstudent #medicalcollege #neetpg2025 #usmleprep #usmlevideos #usmlestep1videos #medicalstudents #neetpgvideos #usmlestep2videos