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We demonstrate how to perform an ultrasound-guided arterial line insertion with a 20 G IV catheter and the out-of-plane bevel-guided technique. This technique allows for continuous visualization of the needle from skin to vessel. We also demonstrate exchange of the 20 G IV catheter for an indwelling catheter via the Seldinger technique. -- Technique demonstrated by Omar Hyder, MD. -- Equipment: Arrow Arterial Catheterization Kit Custom Ref ASK-04125-MGH GE Logiq E Ultrasound Machine -- Disclaimer: Invasive medical procedures can result in harm to patients and practitioners and should be performed only by qualified medical professionals. This video is intended solely for informational purposes and to supplement, not replace, proper training and supervision by qualified instructors. Viewers are advised to check the most current information provided by the manufacturer for every device being used, and to verify the indications, contraindications and proper procedural technique. The dose, method of administration, and contraindications for any administered drug should be confirmed before use. The authors of the video do not assume any liability for any injury or damage to any person or property arising from the use of this video.