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Christian P. Pavlovich, MD, Bernard L. Schwartz Distinguished Professor in Urologic Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland, provides a detailed overview of serum and urinary biomarkers for prostate cancer diagnosis and prognosis. In this 15-minute presentation, Dr. Pavlovich advocates for personalized approaches that leverage biomarkers, genetic insights, and advanced predictive tools to improve prostate cancer detection and reduce unnecessary interventions. Dr. Pavlovich highlights biomarkers such as PHI, 4KScore, IsoPSA, SelectMDx, MyProstateScore, and ExoDx Prostate Test (EPI) that offer improved specificity in identifying clinically significant prostate cancer. Risk calculators like the PCPT, ERSPC, and PBCG provide individualized risk assessments and can guide clinical decisions. Dr. Pavlovich encourages using online calculators for improved accuracy in predicting biopsy outcomes. He also introduces emerging genomic tests, polygenic risk scores, and comprehensive platforms like Stockholm3 that integrate biomarkers, clinical data, and genetics. In addition, combining biomarkers with MRI and clinical information enhances diagnostic accuracy. #prostatecancer #biomarkers #cancerscreening Don't forget to join the GRU Community: https://grandroundsinurology.com/regi... Follow us on Twitter/X: https://x.com/GRUrology And like and subscribe to us here on YouTube!